PERMANENT RULES
Effective Date of Rule: Thirty-one days after filing.
Purpose: Amend WAC 260-70-680 Uniform classification guidelines.
Citation of Existing Rules Affected by this Order: Amending WAC 260-70-680.
Statutory Authority for Adoption: RCW 67.16.020 and 67.16.040.
Adopted under notice filed as WSR 07-03-143 on January 23, 2007.
Number of Sections Adopted in Order to Comply with Federal Statute: New 0, Amended 0, Repealed 0; Federal Rules or Standards: New 0, Amended 0, Repealed 0; or Recently Enacted State Statutes: New 0, Amended 0, Repealed 0.
Number of Sections Adopted at Request of a Nongovernmental Entity: New 0, Amended 0, Repealed 0.
Number of Sections Adopted on the Agency's Own Initiative: New 0, Amended 1, Repealed 0.
Number of Sections Adopted in Order to Clarify, Streamline, or Reform Agency Procedures: New 0, Amended 11 [1], Repealed 0.
Number of Sections Adopted Using Negotiated Rule Making: New 0, Amended 1, Repealed 0; Pilot Rule Making: New 0, Amended 0, Repealed 0; or Other Alternative Rule Making: New 0, Amended 0, Repealed 0.
Date Adopted: March 9 [8], 2007.
R. J. Lopez
Deputy Secretary
OTS-8902.4
AMENDATORY SECTION(Amending WSR 06-09-009, filed 4/10/06,
effective 5/11/06)
WAC 260-70-680
Uniform classification guidelines.
((The
following outline describes the types of substances placed in
each category. This list shall be publicly posted in the
offices of the official veterinarian and the racing secretary.
(1) Class 1
Opiates, opium derivatives, synthetic opioids, psychoactive drugs, amphetamines and U.S. Drug Enforcement Agency (DEA) scheduled I and II drugs. Also found in this class are drugs which are potent stimulants of the nervous system. Drugs in this class have no generally accepted medical use in the racehorse and their pharmacological potential for altering the performance of a race is very high.
(2) Class 2
Drugs in this category have a high potential for affecting the outcome of a race. Most are not generally accepted as therapeutic agents in the racehorse. Many are products intended to alter consciousness or the psychic state of humans, and have no approved or indicated use in the horse. Some, such as injectable local anesthetics, have legitimate use in equine medicine, but should not be found in a racehorse. The following groups of drugs are in this class:
(a) Opiate partial agonists, or agonist-antagonists;
(b) Nonopiate psychotropic drugs, which may have stimulant, depressant, analgesic or neuroleptic effects;
(c) Miscellaneous drugs which might have a stimulant effect on the central nervous system (CNS);
(d) Drugs with prominent CNS depressant action;
(e) Antidepressant and antipsychotic drugs, with or without prominent CNS stimulatory or depressant effects;
(f) Muscle blocking drugs, which have a direct neuromuscular blocking action;
(g) Local anesthetics which have a reasonable potential for use as nerve blocking agents (except procaine); and
(h) Snake venoms and other biologic substances, which may be used as nerve blocking agents.
(3) Class 3
Drugs in this class may or may not have an accepted therapeutic use in the horse. Many are drugs that affect the cardiovascular, pulmonary and autonomic nervous systems. They all have the potential of affecting the performance of a racehorse. The following groups of drugs are in this class:
(a) Drugs affecting the autonomic nervous system which do not have prominent CNS effects, but which do have prominent cardiovascular or respiratory system effects (bronchodilators are included in this class);
(b) A local anesthetic, which has nerve blocking potential but also has a high potential for producing urine residue levels from a method of use not related to the anesthetic effect of the drug (procaine);
(c) Miscellaneous drugs with mild sedative action, such as the sleep inducing antihistamines;
(d) Primary vasodilating/hypotensive agents; and
(e) Potent diuretics affecting renal function and body fluid composition.
(4) Class 4
This category is comprised primarily of therapeutic medications routinely used in racehorses. These may influence performance, but generally have a more limited ability to do so. Groups of drugs assigned to this category include the following:
(a) Nonopiate drugs which have a mild central analgesic effect;
(b) Drugs affecting the autonomic nervous system, which do not have prominent CNS, cardiovascular or respiratory effects;
(i) Drugs used solely as topical vasoconstrictors or decongestants,
(ii) Drugs used as gastrointestinal antispasmodics,
(iii) Drugs used to void the urinary bladder,
(iv) Drugs with a major effect on CNS vasculature or smooth muscle of visceral organs.
(v) Antihistamines, which do not have a significant CNS depressant effect (this does not include H1 blocking agents, which are listed in Class 5);
(c) Mineralocorticoid drugs;
(d) Skeletal muscle relaxants;
(e) Anti-inflammatory drugs--those that may reduce pain as a consequence of their anti-inflammatory actions, which include:
(i) Nonsteroidal anti-inflammatory drugs (NSAIDs);
(ii) Corticosteroids (glucocorticoids); and
(iii) Miscellaneous anti-inflammatory agents.
(f) Anabolic and/or androgenic steroids and other drugs;
(g) Less potent diuretics;
(h) Cardiac glycosides and antiarrhythmics including:
(i) Cardiac glycosides;
(ii) Antiarrhythmic agents (exclusive of lidocaine, bretylium and propranolol); and
(iii) Miscellaneous cardiotonic drugs.
(i) Topical anesthetics--agents not available in injectable formulations;
(j) Antidiarrheal agents; and
(k) Miscellaneous drugs including:
(i) Expectorants with little or no other pharmacologic action;
(ii) Stomachics; and
(iii) Mucolytic agents.
(5) Class 5
Drugs in this category are therapeutic medications for which concentration limits have been established as well as certain miscellaneous agents. Included specifically are agents, which have very localized action only, such as anti-ulcer drugs and certain antiallergic drugs. The anticoagulant drugs are also included.)) This section classifies each drug/medication/foreign substance, and where appropriate and/or available, its trade name. The penalties for violation of this section are in WAC 260-84-110.
(1) Class 1
Class 1 drugs are stimulant and depressant drugs that have the highest potential to affect the performance of a horse, and have no generally accepted medical use. Many of these agents are Drug Enforcement Agency (DEA) Schedule II substances. These include the following drugs and their metabolites: Opiates, opium derivatives, synthetic opioids and psychoactive drugs, amphetamines and amphetamine-like drugs as well as related drugs, including but not limited to apomorphine, nikethamide, mazindol, pemoline, and pentylenetetrazol.
| Drug | Trade Name |
| Alfentanil | Alfenta |
| Amphetamine | |
| Anileridine | Leritine |
| Apomorphine | |
| Benzylpiperazine (BZP) | |
| Carfentanil | |
| Cocaine | |
| Dextromoramide | Palfium, Narcolo |
| Diamorphine | |
| Endorphins | |
| Enkephalins | |
| Ethylmorphine | Dionin |
| Etorphine HCl | M99 |
| Fentanyl | Sublimaze |
| Hydromorphone | Dilaudid |
| Hydroxyamphetamine | Paradrine |
| Levorphanol | Levo-Dremoran |
| Lofentanil | |
| Mazindol | Sanorex |
| Meperidine | Demerol |
| Mephentermine | |
| Metaraminol | Aramine |
| Methadone | Dolophine |
| Methamphetamine | Desoxyn |
| Methaqualone | Quaalude |
| Methylphenidate | Ritalin |
| Metopon (methyldihydromorphinone) | |
| Morphine | |
| Nikethamide | Coramine |
| Oxycodone | Percodan |
| Oxymorphone | Numorphan |
| Pemoline | Cylert |
| Pentylenetetrazol | Metrazol, Nioric |
| Phenazocine | Narphen |
| Phencyclidine (PCP) | Sernylan |
| Phendimetrazine | Bontril, etc. |
| Phenmetrazine | Preludin |
| Picrotoxin | |
| Piritramide | |
| Remifentanil | Ultiva |
| Strychnine | |
| Sufentanil | Sufenta |
Class 2 drugs are drugs/medication/foreign substances that have a high potential to affect the performance of a horse, but less of a potential than class 1 drugs. Class 2 drugs are either not generally accepted as therapeutic agents in racing horses, or are therapeutic agents that have a high potential for abuse.
| Drug | Trade Name |
| Acecarbromal | |
| Acetophenazine | Tindal |
| Adinazolam | |
| Alcuronium | Alloferin |
| Alphaprodine | Nisentil |
| Alpidem | Anaxyl |
| Alprazolam | Xanax |
| Althesin | Saffan |
| Amisulpride | Solian |
| Amitriptyline | Elavil, Amitril, Endep |
| Amobarbital | Amytal |
| Amoxapine | Asendin |
| Amperozide | |
| Anilopam | Anisine |
| Aprobarbital | Alurate |
| Azacylonol | Frenque |
| Azaperone | Stresnil, Suicalm, Fentaz (with Fentanyl) |
| Barbital | Veronal |
| Barbiturates | |
| Bemegride | Megimide, Mikedimide |
| Benperidol | |
| Bentazepam | Tiadipona |
| Benzactizine | Deprol, Bronchodiletten |
| Benzoctamine | |
| Benzodiazepines | |
| Benzphetamine | Didrex |
| Benztropine | Cogentin |
| Biriperone | |
| Bromazepam | Lexotan, Lectopam |
| Bromisovalum | Diffucord, etc. |
| Bromocriptine | Parlodel |
| Bromperidol | Bromidol |
| Brotizolam | Brotocol |
| Bupivacaine | Marcaine |
| Buprenorphine | Temgesic |
| Buspirone | Buspar |
| Buspropion | Wellbutrin |
| Butabarbital (Secbutobarbitone) | Butacaps, Butasol, etc. |
| Butalbital (Talbutal) | Fiorinal |
| Butanilicaine | Hostacain |
| Butaperazine | Repoise |
| Butoctamide | Listomin |
| Caffeine | |
| Camazepam | Paxor |
| Captodiame | Covatine |
| Carbidopa + levodopa | Sinemet |
| Carbromol | Mifudorm |
| Carphenazine | Proketazine |
| Carpipramine | Prazinil |
| Chloralose (Alpha-Chloralose) | |
| Chloral betaine | Beta-Chlor |
| Chloral hydrate | Nactec, Oridrate, etc. |
| Chloraldehyde (chloral) | |
| Chlordiazepoxide | Librium |
| Chlormezanone | Trancopal |
| Chloroform | |
| Chlorhexidol | |
| Chloroprocaine | Nesacaine |
| Chlorproethazine | Newiplege |
| Chlorpromazine | Thorazine, Largactil |
| Chlorprothixene | Taractan |
| Citalopram | Celex |
| Clobazam | Urbanyl |
| Clocapramine | |
| Clomethiazole | |
| Clomipramine | Anafranil |
| Clonazepam | Klonopin |
| Clorazepate | Tranxene |
| Clothiapine | Entermin |
| Clotiazepam | Trecalmo, Rize |
| Cloxazolam | Enadel, Sepazon, Tolestan |
| Clozapine | Clozaril, Leponex |
| Codeine | |
| Conorphone | |
| Corticaine | Ultracain |
| Crotetamide | |
| Cyamemazine | Tercian |
| Cyclobarbital | Phanodorm |
| Decamethonium | Syncurine |
| Demoxepam | |
| Desipramine | Norpromine, Pertofrane |
| Dezocine | Dalgan¦ |
| Diazepam | Valium |
| Dichloralphenazone | Febenol, Isocom |
| Diethylpropion | Tepanil, etc. |
| Diethylthiambutene | Themalon |
| Dihydrocodeine | Parcodin |
| Dilorazepam | Briantum |
| Diprenorphine | M50/50 |
| Dixyrazine | Esucos |
| Dopamine | Intropin |
| Doxapram | Dopram |
| Doxefazepam | Doxans |
| Doxepin | Adapin, Sinequan |
| Droperidol | Inapsine, Droleptan, Innovar-Vet (with Fentanyl) |
| Enciprazine | |
| Ephedrine | |
| Epinephrine | |
| Erythropoietin (EPO) | Epogen, Procrit, etc. |
| Estazolam | Domnamid, Eurodin, Nuctalon |
| Ethamivan | |
| Ethchlorvynol | Placidyl |
| Ethinamate | Valmid |
| Ethopropazine | Parsidol |
| Ethylisobutrazine | Diquel |
| Etidocaine | Duranest |
| Etifoxin | Stresam |
| Etizolam | Depas, Pasaden |
| Etodroxizine | Indunox |
| Etomidate | |
| Fenarbamate | Tymium |
| Fenfluramine | Pondimin |
| Fluanisone | Sedalande |
| Fludiazepam | Erispam |
| Flunitrazepam | Rohypnol, Narcozep, Darkene, Hypnodorm |
| Fluopromazine | Psyquil, Siquil |
| Fluoresone | Caducid |
| Fluoxetine | Prozac |
| Flupenthixol | Depixol, Fluanxol |
| Fluphenazine | Prolixin, Permitil, Anatensol |
| Flurazepam | Dalmane |
| Fluspirilene | Imap, Redeptin |
| Flutoprazepam | Restas |
| Fluvoxamine | Dumirox, Faverin, etc. |
| Gallamine | Flaxedil |
| Gepirone | |
| Glutethimide | Doriden |
| Halazepam | Paxipam |
| Haloperidol | Haldol |
| Haloxazolam | Somelin |
| Hemoglobin glutamers | Oxyglobin, Hemopure |
| Hexafluorenium | Myalexen |
| Hexobarbital | Evipal |
| Homophenazine | Pelvichthol |
| Hydrocodone (dihydrocodeinone) | Hycodan |
| Hydroxyzine | Atarax |
| Ibomal | Noctal |
| Imipramine | Imavate, Presamine, Tofranil |
| Isapirone | |
| Isocarboxazid | Marplan |
| Isomethadone | |
| Isoproterenol | Isoprel |
| Ketamine | Ketalar, Ketaset, Vetalar |
| Ketazolam | Anxon, Laftram, Solatran, Loftran |
| Lenperone | Elanone-V |
| Levomethorphan | |
| Lidocaine | Xylocaine |
| Lithium | Lithizine, Duralith, etc. |
| Lobeline | |
| Loflazepate, Ethyl | Victan |
| Loprazolam | Dormonort, Havlane |
| Lorazepam | Ativan |
| Lormetazepam | Noctamid |
| Loxapine | Laxitane |
| Maprotiline | Ludiomil |
| Mebutamate | Axiten, Dormate, Capla |
| Meclofenoxate | Lucidiril, etc. |
| Medazepam | Nobrium, etc. |
| Melperone | Eunerpan |
| Meparfynol | Oblivon |
| Mepazine | Pacatal |
| Mephenoxalone | Control, etc. |
| Mephenytoin | Mesantoin |
| Mephobarbital (Methylphenobarbital) | Mebaral |
| Mepivacaine | Carbocaine |
| Meprobamate | Equanil, Miltown |
| Mesoridazine | Serentil |
| Metaclazepam | Talis |
| Metazocine | |
| Metharbital | Gemonil |
| Methohexital | Brevital |
| Methotrimeprazine | Levoprome, Neurocil, etc. |
| Methyprylon | Noludar |
| Metocurine | Metubine |
| Metomidate | Hypnodil |
| Mexazolam | Melex |
| Midazolam | Versed |
| Mirtazepine | Remeron |
| Modafinil | Provigil |
| Molindone | Moban |
| Moperone | Luvatren |
| Mosaprimine | |
| Nalbuphine | Nubain |
| Nalorphine | Nalline, Lethidrone |
| Nefazodone | Serzone |
| Nimetazepam | Erimin |
| Nitrazepam | Mogadon |
| Nordiazepam | Calmday, Nordaz, etc. |
| Norepinephrine | |
| Nortriptyline | Aventyl, Pamelor |
| Olanzepine | Zyprexa |
| Oxazepam | Serax |
| Oxazolam | Serenal |
| Oxyperitine | Forit, Integrin |
| Pancuronium | Pavulon |
| Paraldehyde | Paral |
| Paroxetine | Paxil, Seroxat |
| Penfluridol | Cyperon |
| Pentobarbital | Nembutal |
| Perazine | Taxilan |
| Periciazine | Alodept, etc. |
| Perlapine | Hypnodin |
| Perphenazine | Trilafon |
| Phenaglycodol | Acalo, Alcamid, etc. |
| Phenelzine | Nardelzine, Nardil |
| Phenobarbital | Luminal |
| Phentermine | Iomamin |
| Piminodine | Alvodine, Cimadon |
| Pimozide | Orap |
| Pinazepam | Domar |
| Pipamperone | Dipiperon |
| Pipequaline | |
| Piperacetazine | Psymod, Quide |
| Piperocaine | Metycaine |
| Pipotiazine | Lonseren, Piportil |
| Pipradrol | Dataril, Gerondyl, etc. |
| Piquindone | |
| Prazepam | Verstran, Centrax |
| Prilocaine | Citanest |
| Prochlorperazine | Darbazine, Compazine |
| Propanidid | |
| Propiomazine | Largon |
| Propionylpromazine | Tranvet |
| Propiram | |
| Propofol | Diprivan, Disoprivan |
| Propoxycaine | Ravocaine |
| Prothipendyl | Dominal |
| Protriptyline | Concordin, Triptil |
| Proxibarbital | Axeen, Centralgol |
| Pyrithyldione | Hybersulfan, Sonodor |
| Quazipam | Doral |
| Quetiapine | Seroquel |
| Racemethorphan | |
| Racemorphan | |
| Raclopride | |
| Remoxipride | Roxiam |
| Reserpine | Serpasil |
| Rilmazafone | |
| Risperidone | |
| Ritanserin | |
| Rivastigmine | Exelon |
| Romifidine | Sedivet |
| Ropivacaine | Naropin |
| Secobarbital (Quinalbarbitone) | Seconal |
| Selegiline | Eldepryl, Jumex |
| Sertraline | Lustral, Zoloft |
| Snake Venoms | |
| Spiclomazine | |
| Spiperone | |
| Succinylcholine | Sucostrin, Quelin, etc. |
| Sulfondiethylmethane | |
| Sulfonmethane | |
| Sulforidazine | Inofal |
| Sulpiride | Aiglonyl, Sulpitil |
| Sultopride | Barnetil |
| Talbutal | Lotusate |
| Tandospirone | |
| Temazepam | Restoril |
| Tetrabenazine | Nitoman |
| Tetracaine | Pontocaine |
| Tetrazepam | Musaril, Myolastin |
| Thebaine | |
| Thialbarbital | Kemithal |
| Thiamylal | Surital |
| Thiethylperazine | Torecan |
| Thiopental | Pentothal |
| Thiopropazate | Dartal |
| Thioproperazine | Majeptil |
| Thioridazine | Mellaril |
| Thiothixene | Navane |
| Tiapride | Italprid, Luxoben, etc. |
| Tiletamine | Component of Telazol |
| Timiperone | Tolopelon |
| Tofisopam | Grandaxain, Seriel |
| Topirimate | Topamax |
| Tramadol | Ultram |
| Tranylcypromine | Parnate |
| Trazodone | Desyrel |
| Triazolam | Halcion |
| Tribromethanol | |
| Tricaine methanesulfonate | Finquel |
| Trichloroethanol | |
| Tricholoethylene | Trilene, Trimar |
| Triclofos | Triclos |
| Trifluomeprazine | Nortran |
| Trifluoperazine | Stelazine |
| Trifluperidol | Triperidol |
| Triflupromazine | Vetame, Vesprin |
| Trimipramine | Surmontil |
| Tubocurarine (Curare) | Metubin |
| Tybamate | Benvil, Nospan, etc. |
| Urethane | |
| Valnoctamide | Nirvanyl |
| Venlafaxine | Effexor |
| Veralipride | Accional, Veralipril |
| Vercuronium | Norcuron |
| Viloxazine | Catatrol, Vivalan, etc. |
| Vinbarbital | Delvinol |
| Vinylbital | Optanox, Speda |
| Yohimbine | |
| Zolazepam | |
| Zolpidem | Ambien, Stilnox |
| Zopiclone | Imovan |
| Zotepine | Lodopin |
| Zuclopenthixol | Ciatyl, Cesordinol |
Class 3 drugs are drugs/medication/foreign substances that may or may not have generally accepted medical use in the racing horse, but the pharmacology of which suggests less potential to affect performance than class 2 drugs.
| Drug | Trade Name |
| Acebutolol | Sectral |
| Acepromazine | Atrovet, Notensil, PromAce¦ |
| Albuterol (Salbutamol) | Proventil, Ventolin |
| Alprenolol | |
| Ambenonium | Mytelase, Myeuran |
| Aminophylline | Aminophyllin, etc. |
| Amlodipine | Norvasc |
| Amyl nitrite | |
| Arecoline | |
| Atenolol | Tenormin |
| Atropine | |
| Betaxolol | Kerlone |
| Bethanidine | Esbatal |
| Biperiden | Akineton |
| Bisoprolol | Zebeta, Bisobloc, etc. |
| Bitolterol | Effectin |
| Bretylium | Bretylol |
| Brimonidine | Alphagan |
| Bromfenac | Duract |
| Bromodiphenhydramine | |
| Bumetanide | Bumex |
| Butorphanol | Stadol, Torbugesic |
| Candesartan | Atacand |
| Captopril | Capolen |
| Carazolol | Carbacel, Conducton |
| Carbachol | Lentin, Doryl |
| Carbamezapine | Tegretol |
| Carbinoxamine | Clistin |
| Carteolol | Cartrol |
| Carvedilol | Coreg |
| Cimeterol | |
| Clenbuterol | Ventipulmin |
| Clonidine | Catapres |
| Cyclandelate | Cyclospasmol |
| Cycrimine | Pagitane |
| Detomidine | Dormosedan |
| Dextropropoxyphene | Darvon |
| Diazoxide | Proglycem |
| Dimefline | |
| Diphenhydramine | Benadryl |
| Dipyridamole | Persantine |
| Dobutamine | Dobutrex |
| Doxylamine | Decapryn |
| Dyphylline | |
| Edrophonium | Tensilon |
| Enalapril (metabolite enaloprilat) | Vasotec |
| Erthrityl tetranitrate | Cardilate |
| Esmolol | Brevibloc |
| Etamiphylline | |
| Ethacrynic acid | Edecrin |
| Ethylnorepinephrine | Bronkephrine |
| Fenoldopam | Corlopam |
| Fenoterol | Berotec |
| Fenspiride | Respiride, Respan, etc. |
| Flupirtine | Katadolone |
| Formoterol | Altram |
| Gabapentin | Neurontin |
| Glycopyrrolate | Robinul |
| Guanadrel | Hylorel |
| Guanethidine | Ismelin |
| Guanabenz | Wytensin |
| Heptaminol | Corofundol |
| Homatropine | Homapin |
| Hydralazine | Apresoline |
| Ipratropium | |
| Irbesarten | Avapro |
| Isoetharine | Bronkosol |
| Isosorbide dinitrate | Isordil |
| Ketorolac | Toradol |
| Labetalol | Normodyne |
| Losartan | Hyzaar |
| Mabuterol | |
| Mecamylamine | Inversine |
| Medetomidine | Domitor |
| Metaproterenol | Alupent, Metaprel |
| Methachloline | |
| Methixene | Trest |
| Methoxamine | Vasoxyl |
| Methoxyphenamine | Orthoxide |
| Methylatropine | |
| Methyldopa | Aldomet |
| Metolazone | |
| Metoprolol | Lopressor |
| Mibefradil | Posicor |
| Midodrine | Pro-Amiline |
| Minoxidil | Loniten |
| Moexipril (metabolite moexiprilat) | Uniretic |
| Muscarine | |
| Nadol | Corgard |
| Naratriptan | Amerge |
| Nefopam | |
| Neostigmine | Prostigmine |
| Nitroglycerin | |
| Oxprenolol | Trasicor |
| Papaverine | Pavagen, etc. |
| Paramethadione | Paradione |
| Pargyline | Eutonyl |
| Penbutolol | Levatol |
| Pentaerythritol tetranitrate | Duotrate |
| Pentazocine | Talwin |
| Phenoxybenzamine | Dibenzyline |
| Phentolamine | Regitine |
| Phenylephrine | Isophrin, Neo-Synephrine |
| Phenylpropanolamine | Propadrine |
| Physostigmine | Eserine |
| Pindolol | Viskin |
| Pirbuterol | Maxair |
| Piretanide | Arelix, Tauliz |
| Prazosin | Minipress |
| Primidone | Mysoline |
| Procaine | |
| Procaterol | Pro Air |
| Procyclidine | Kemadrin |
| Promazine | Sparine |
| Promethazine | Phenergan |
| Propentophylline | Karsivan |
| Propranolol | Inderal |
| Protokylol | Ventaire |
| Pseudoephedrine | Cenafed, Novafed |
| Pyridostigmine | Mestinon, Regonol |
| Pyrilamine | Neoantergan, Equihist |
| Ractopamine | Raylean |
| Ritodrine | Yutopar |
| Rizatriptan | Maxalt |
| Salmeterol | |
| Scopolamine (Hyoscine) | Triptone |
| Sibutramine | Meridia |
| Sotalol | Betapace, Sotacor |
| Sumatriptan | Imitrex |
| Telmisartin | Micardis |
| Terbutaline | Brethine, Bricanyl |
| Testolactone | Teslac |
| Theophylline | Aqualphyllin, etc. |
| Timolol | Blocardrin |
| Tolazoline | Priscoline |
| Torsemide (Torasemide) | Demadex |
| Trandolapril (and metabolite, Trandolaprilat) | Tarka |
| Trihexylphenidyl | Artane |
| Trimethadione | Tridione |
| Trimethaphan | Arfonad |
| Tripelennamine | PBZ |
| Valsartan | Diovan |
| Xylazine | Rompun, Bay Va 1470 |
| Zolmitriptan | Zomig |
| Zonisamide | Zonegran |
Class 4 drugs include therapeutic drugs/medications/foreign substances that would be expected to have less potential to affect the performance of a racing horse than class 3 drugs.
| Drug | Trade Name |
| Acetaminophen (Paracetamol) | Tylenol, Tempra, etc. |
| Acetanilid | |
| Acetazolamide | Diamox, Vetamox |
| Acetophenetidin (Phenacetin) | |
| Acetylsalicylic acid (Aspirin) | |
| Alclofenac | |
| Aclomethasone | Aclovate |
| Aldosterone | Aldocortin, Electrocortin |
| Ambroxol | Ambril, etc. |
| Amcinonide | Cyclocort |
| Aminocaproic acid | Amicar, Caprocid |
| Aminodarone | |
| 2-Aminoheptaine | Tuamine |
| Aminopyrine | |
| Amisometradine | Rolictron |
| Amlopidine | Norvasc, Ammivin |
| Amrinone | |
| Anisotropine | Valpin |
| Antipyrine | |
| Apazone (Azapropazone) | Rheumox |
| Aprindine | |
| Baclofen | Lioresal |
| Beclomethasone | Propaderm |
| Benazepril | Lotrel |
| Bendroflumethiazide | Naturetin |
| Benoxaprofen | |
| Benoxinate | Dorsacaine |
| Benzocaine | |
| Benzthiazide | |
| Bepridil | Bepadin |
| Betamethasone | Betasone, etc. |
| Bethanechol | Urecholine, Duvoid |
| Boldenone | Eq |